Description

KLOW Blend 80 mg — Quad Peptide Combination for Recovery, Skin & Anti-Inflammatory Research

The KLOW Blend combines four complementary research peptides — KPV (an anti-inflammatory tripeptide), GHK-Cu (copper tripeptide), BPC-157 (body protection compound), and TB-500 (thymosin beta-4 fragment) — in a single vial. This expanded formulation builds on the GLOW Blend by adding KPV’s melanocortin-derived anti-inflammatory activity, offering researchers a multi-pathway tool for investigations into tissue repair, inflammatory modulation, skin remodeling, and cellular regeneration.

What It Is

• Class: Combined four-peptide blend — anti-inflammatory tripeptide + copper-binding tripeptide + cytoprotective pentadecapeptide + actin-sequestering peptide fragment
• Concept: Four peptides addressing overlapping pathways: KPV modulates inflammation through melanocortin signaling, GHK-Cu drives copper-mediated tissue remodeling, BPC-157 supports cytoprotection and angiogenesis, and TB-500 promotes cell migration and tissue regeneration.
• Format: Research-grade synthetic peptide blend supplied as a lyophilized powder.

Proposed Mechanisms (Preclinical)

Anti-Inflammatory Pathways (KPV)

• Derived from the C-terminal sequence of α-MSH (alpha-melanocyte-stimulating hormone).
• Modulates NF-κB signaling and pro-inflammatory cytokine pathways in research models.
• Investigations into mucosal inflammation in gut and skin tissue models.

Skin & Collagen Pathways (GHK-Cu)

• Binds copper ions (Cu²⁺) to form a bioactive complex influencing tissue remodeling.
• Supports collagen and elastin synthesis in dermal fibroblast research.
• Engages antioxidant signaling in skin and connective tissue models.

Cytoprotection & Vascular Effects (BPC-157)

• Promotes VEGF expression and neovascularization at injury sites.
• Supports fibroblast activity and collagen deposition during tissue remodeling.
• Research into mucosal and connective-tissue cytoprotection.

Cellular Migration & Repair (TB-500)

• Acts on the actin cytoskeleton, supporting cellular migration to sites of injury.
• Investigations into endothelial cell proliferation and capillary formation.
• Studies on accelerated wound closure and tissue regeneration.

Selected Research Highlights

• Inflammatory Bowel Research: KPV has been investigated for effects on colitis and inflammatory bowel disease models, particularly via mucosal anti-inflammatory pathways.
• Wound Healing Studies: Multi-peptide approaches examining accelerated closure of dermal and connective-tissue wounds in animal models.
• Tendon & Soft Tissue Repair: Research on combined effects across tendon, ligament, and muscle injury models.
• Skin & Anti-Aging Studies: GHK-Cu and KPV have been investigated for skin elasticity, dermal density, and inflammatory skin condition markers.

Chemical & Handling Information

• Type: Combined synthetic peptide blend
• Components: KPV (Lysine-Proline-Valine tripeptide, derived from α-MSH 11–13), GHK-Cu (copper-bound glycyl-histidyl-lysine), BPC-157 (15-amino-acid gastric-derived peptide), TB-500 (synthetic fragment of thymosin beta-4) — exact ratios per lot specification
• Appearance: Lyophilized powder with a faint blue tint from the copper-bound GHK-Cu component
• Solubility: Reconstitutes readily in bacteriostatic water or sterile saline for laboratory preparation

Specifications

• Peptide Blend: KPV + GHK-Cu + BPC-157 + TB-500
• Amount: 80 mg total per vial
• Form: Lyophilized powder
• Purity: ≥99% (HPLC); COA per lot available
• Packaging: Sealed glass vials with rubber stopper and aluminum crimp seal, suitable for standard laboratory handling

Storage & Stability

• Store lyophilized vials in a cool, dry place, protected from light.
• Refrigeration or freezing of the lyophilized peptide is recommended for extended stability, in accordance with standard laboratory SOPs.
• After reconstitution, store at 2–8 °C for short-term laboratory use (typically up to 30 days).
• For long-term storage of reconstituted material, aliquot and freeze at −20 °C or below.
• Avoid repeated freeze-thaw cycles, which can degrade peptide integrity.

Research Use Disclaimer

This product is sold strictly for laboratory research use only. Not intended for human or animal consumption. Not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease or condition. Customers are solely responsible for the lawful handling, storage, and use of this product in accordance with all applicable laws and regulations.