Description

GHK-Cu 50 mg — Copper Tripeptide for Skin, Collagen & Tissue Remodeling Research

GHK-Cu is a naturally occurring copper-binding tripeptide composed of glycine, histidine, and lysine (Gly-His-Lys) bound to a copper ion (Cu²⁺). In preclinical research, GHK-Cu has been extensively studied for its effects on skin remodeling, collagen and elastin synthesis, wound healing, antioxidant activity, and hair follicle research, and is one of the most well-characterized copper-binding peptides in scientific literature.

What It Is

• Class: Copper-binding tripeptide complex
• Concept: A bioactive copper-peptide complex that influences gene expression related to tissue remodeling, with documented effects on collagen production, antioxidant pathways, and cellular regeneration in research models.
• Format: Research-grade synthetic peptide supplied as a lyophilized powder.

Proposed Mechanisms (Preclinical)

Copper Transport & Gene Modulation

• Acts as a copper-delivery vehicle to cells, supporting copper-dependent enzymatic activity.
• Modulates expression of genes related to extracellular matrix remodeling, including collagen and glycosaminoglycan synthesis.
• Influences activity of matrix metalloproteinases (MMPs) involved in tissue turnover.

Skin, Collagen & Antioxidant Effects

• Research explores stimulation of dermal fibroblast activity and collagen Type I, II, and III synthesis.
• Investigations into elastin and proteoglycan production in skin remodeling research.
• Studies on antioxidant signaling, including superoxide dismutase activity.
• Examination of hair follicle research, including dermal papilla cell activity and follicle size markers.

Selected Research Highlights

• Skin Remodeling Studies: GHK-Cu has been investigated for effects on skin elasticity, wrinkle depth, dermal density, and barrier function in research models.
• Wound Healing Research: Studies examining accelerated closure of dermal wounds, including in compromised healing models such as diabetic-pattern wounds.
• Anti-Aging Pathway Research: Investigations into gene expression changes associated with cellular senescence and tissue rejuvenation markers.
• Hair Research: Animal studies examining effects on hair follicle size, hair growth phase regulation, and dermal papilla activity.

Chemical & Handling Information

• Type: Copper-binding tripeptide complex
• Backbone: Glycyl-L-Histidyl-L-Lysine (Gly-His-Lys) bound to copper(II) ion (exact specification per lot)
• Appearance: Blue lyophilized powder (color attributed to the copper-peptide complex)
• Solubility: Reconstitutes readily in bacteriostatic water or sterile saline for laboratory preparation

Specifications

• Peptide: GHK-Cu (Copper Tripeptide-1)
• Amount: 50 mg per vial
• Form: Lyophilized powder
• Purity: ≥99% (HPLC); COA per lot available
• Packaging: Sealed glass vials with rubber stopper and aluminum crimp seal, suitable for standard laboratory handling

Storage & Stability

• Store lyophilized vials in a cool, dry place, protected from light.
• Refrigeration or freezing of the lyophilized peptide is recommended for extended stability, in accordance with standard laboratory SOPs.
• After reconstitution, store at 2–8 °C for short-term laboratory use (typically up to 30 days).
• For long-term storage of reconstituted material, aliquot and freeze at −20 °C or below.
• Avoid repeated freeze-thaw cycles, which can degrade peptide integrity.

Research Use Disclaimer

This product is sold strictly for laboratory research use only. Not intended for human or animal consumption. Not approved by the FDA for the diagnosis, treatment, cure, or prevention of any disease or condition. Customers are solely responsible for the lawful handling, storage, and use of this product in accordance with all applicable laws and regulations.